CE · ISO 13485 · GMP · Class III

Why hurt,
when you can
prevent it?

ORTOBRAND INTERNATIONAL manufactures innovative hyaluronic acid-based orthopedic medical devices for patients with osteoarthritis and tendon disorders.

ORTHOFLEX — enjoy your life
About Us

ORTOBRAND
INTERNATIONAL

A global healthcare company dedicated to improving lives.

ORTOBRAND INTERNATIONAL is a Romanian multinational company engaged in research, development, manufacturing, marketing and sales of innovative hyaluronic acid (HA) based orthopedic medical devices for patients suffering from osteoarthritis and tendon disorders.

Our products are produced under Good Manufacturing Practice (GMP), accredited to EU standards by the NSAI (National Standards Authority of Ireland), and are CE and ISO 13485 certified — listed as Class III medical devices in accordance with the European Medical Devices Directive.

CE Marked
ISO 13485
GMP Certified
Class III Device
💧

Viscosupplementation

Restoring natural joint lubrication by supplementing or replacing synovial fluid with hyaluronic acid — reducing friction, relieving pain, and improving mobility.

🔬

Biofermentation Technology

All HA is produced via biofermentation — eliminating animal-derived sources and any risk of allergic reactions. Sterile autoclave process ensures maximum safety.

🌍

Global Reach

Partnering with specialized companies worldwide to bring innovative orthopedic solutions to more patients across Europe and beyond.

Our Products

ORTHOFLEX® Product Line

Four targeted solutions for joints and tendons — all in prefilled, single-dose syringes.

The Science

Hyaluronic Acid:
Nature's Joint Lubricant

Hyaluronic acid (HA) is a natural glycosaminoglycan found in all tissues and fluids of the body, with the highest concentration in soft connective tissues and synovial joints. It provides lubrication, shock absorption, and nutrient transport.

In osteoarthritic joints, the concentration and molecular weight of HA decreases by 33–50%, impairing joint function. Viscosupplementation with ORTHOFLEX® products restores this balance — delivering analgesic, anti-inflammatory, and chondroprotective effects.

80%
of people over 55 affected by osteoarthritis
33–50%
reduction in natural HA in arthritic joints
3 MilDa
high molecular weight for maximum efficacy
2 yr
shelf life — autoclave sterilized
Testimonials

Trusted by Specialists & Patients

See All Reviews →
★★★★★

"I have been prescribing ORTHOFLEX one to my patients for over two years. The single-injection protocol is a game changer — patients appreciate not having to return for multiple visits."

MI
Dr. Mihai Ionescu
Orthopedic Surgeon, Bucharest
★★★★★

"After years of knee pain, my doctor recommended ORTHOFLEX forte. Within two weeks of completing the 3-injection course I noticed a significant reduction in pain. I can walk much longer distances now."

EP
Elena Popa
Patient, 62 years old
★★★★★

"I regularly use ORTHOFLEX products for my athletic patients. The biofermentation origin means zero allergic reactions — I haven't had a single adverse event."

CF
Dr. Cristian Florescu
Sports Medicine Physician, Timișoara
Contact Us

Get in Touch

For product inquiries, partnerships, or medical information, reach out to our team. We're happy to help.

Email
office@ortobrand.net
Phone
+40 729 891 739
Address
Județ Bihor, Sat Grosi nr. 277
România
WhatsApp